MyBioSource.com's MOUSE ANTI HUMAN CD138:FITC is a Mouse monoclonal antibody. The MOUSE ANTI HUMAN CD138:FITC Antibody was generated using SDC1, Syndecan, and Syndecan 1 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: Flow Cytometry.
Description
Mouse anti human CD138 antibody, clone B-A38 recognizes human CD138, also known as Syndecan-1 (SDC-1). CD138 is a member of the transmembrane heparan sulfate proteoglycan family (O'Connell et al. 2004, Sanderson et al. 2008). It is composed of a core protein (comprising 3 domains; a short cytoplasmic domain, a transmembrane domain, and a long extracellular domain) and covalently attached heparan sulfate chains (Sanderson et al. 2008).Syndecan-1 is expressed on the surface of plasma cells within the hematopoietic system and on the surface of mature epithelial cells (O'Connell et al. 2004). It acts as an extracellular matrix receptor, involved in many cellular functions, including cell binding, cell signalling and cytoskeletal organization through cell-cell adhesion and cell-matrix adhesion (Sanderson et al. 2008)